Appendix (anatomy)

From Ascension Glossary

The Appendix is a blind-ended tube connected to the cecum, from which it develops in the embryo. The cecum is a pouchlike structure of the colon, located at the junction of the small and the large intestines.The human appendix averages 9 cm in length but can range from 2 to 20 cm. The diameter of the appendix is usually between 7 and 8 mm. While the base of the appendix is at a fairly constant location—2 cm below the ileocecal valve, the tip of the appendix can be variably located—in the pelvis, outside the peritoneum or behind the cecum.

Immune and lymphatic system

The appendix has been identified as an important component of mammalian mucosal immune function, particularly B cell mediated immune responses and extrathymically derived T cells. This structure helps in the proper movement and removal of waste matter in the digestive system, contains lymphatic vessels that regulate pathogens, and lastly, might even produce early defences that prevent deadly diseases. Additionally, it is thought that this may provide more immune defences from invading pathogens and getting the lymphatic system's B and T cells to fight the viruses and bacteria that infect that portion of the bowel and training them, so that immune responses are targeted and more able to reliably and less dangerously fight off pathogens. In addition there are different immune cells called innate lymphoid cells that function in the gut, to help the appendix maintain digestive health. [1]

References


See Also

Lymphatic System

RBC Formation

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