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Fluids move throughout the body via several paths. The cardiovascular system circulates blood, nutrients, and gases throughout the body. The lymphatic system carries white blood cells and other immune cells through a network of vessels and tissues, including lymph nodes. The lymphatic system also serves as a connection between tissues and the bloodstream, performing several functions such as removing dead blood cells and other waste. | Fluids move throughout the body via several paths. The cardiovascular system circulates blood, nutrients, and gases throughout the body. The lymphatic system carries white blood cells and other immune cells through a network of vessels and tissues, including lymph nodes. The lymphatic system also serves as a connection between tissues and the bloodstream, performing several functions such as removing dead blood cells and other waste. | ||
The | The [[Brain]], part of the central nervous system, has blood vessels but has been thought to lack lymphatic vessels. Researchers recently discovered a series of channels that surround blood vessels within the brain. This system, managed by the brain's glial cells, was termed the glymphatic system. It moves cerebrospinal fluid, a clear liquid surrounding the brain and spinal cord, quickly and deeply throughout the brain, removing waste.The discovery of a pathway for immune cells to exit the [[CNS|central nervous system]] raises the question of whether disruption of this route may be involved in neurological disorders that are associated with immune system dysfunction, such as multiple sclerosis, meningitis, and Alzheimer’s disease.<ref>[source nih.gov/news-events/nih-research-matters/lymphatic-vessels-discovered-central-nervous-system Lymph CNS discovery]</ref> | ||
==Meninges Immune Cell== | |||
The meningeal lymphatic vessels (or meningeal lymphatics) are a recently discovered network of conventional lymphatic vessels located parallel to the dural sinuses and meningeal arteries of the mammalian central nervous system (CNS). As a part of the lymphatic system, the meningeal lymphatics are responsible for draining immune cells, small molecules, and excess fluid from the [[CNS]] and into the deep cervical lymph nodes. Like peripheral lymphatic vessels, the meningeal lymphatics were shown to serve both the tissue drainage and immune cell trafficking functions of the lymphatic system. In addition, histological analysis revealed that the meningeal lymphatics constitutively contain T cells, B cells, and MHC class II-expressing myeloid cells, demonstrating that meningeal lymphatic vessels are capable of carrying immune cells.<ref>[https://en.wikipedia.org/wiki/Meningeal_lymphatic_vessels Meningeal Lymphatic Vessel]</ref> | |||
==References== | ==References== |