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Since the late 2000s, scientists began to develop techniques known as “genome (or gene) editing.” Genome editing allows scientists to make changes to a specific “target” site in the genome. One of the techniques that have generated the most excitement, due to its efficiency and ease of use, is called “CRISPR.” CRISPR stands for “clustered regularly interspaced short palindromic repeats.” The basis of CRISPR technology is a system that bacteria evolved to protect themselves against viruses. Scientists have now taken components of the CRISPR system and fashioned it into a tool for genome editing. | Since the late 2000s, scientists began to develop techniques known as “genome (or gene) editing.” Genome editing allows scientists to make changes to a specific “target” site in the genome. One of the techniques that have generated the most excitement, due to its efficiency and ease of use, is called “CRISPR.” CRISPR stands for “clustered regularly interspaced short palindromic repeats.” The basis of CRISPR technology is a system that bacteria evolved to protect themselves against viruses. Scientists have now taken components of the CRISPR system and fashioned it into a tool for genome editing. | ||
Gene editing has significant potential to benefit human health. At the same time, it raises profound questions that require public deliberation — what if we make alterations we regret? What if seemingly safe genetic changes prove to have unintended consequences? What are the standards for safety as the medical community seeks to explore these tools in an effort to diminish suffering? Additionally, if as a society we agree that the use of genome editing is acceptable, how do we ensure that all individuals are aware of the potentials of these technologies, and that everyone who wants to access such technologies can afford them? Researchers, bioethicists and policymakers, including a number of the scientists who pioneered CRISPR, have called for caution and the need for public consultation and dialogue that also involves faith leaders, environmental activists, and advocates for patients and for people with disabilities. As society seeks a balance between the desire to realize the benefits of gene editing and a variety of other concerns, pgEd hopes to play a part in facilitating broad conversations that engage all communities and ensure that diverse values and voices are heard. <ref>[https://pged.org/genetic-modification-genome-editing-and-crispr/ Genetic | Gene editing has significant potential to benefit human health. At the same time, it raises profound questions that require public deliberation — what if we make alterations we regret? What if seemingly safe genetic changes prove to have unintended consequences? What are the standards for safety as the medical community seeks to explore these tools in an effort to diminish suffering? Additionally, if as a society we agree that the use of genome editing is acceptable, how do we ensure that all individuals are aware of the potentials of these technologies, and that everyone who wants to access such technologies can afford them? Researchers, bioethicists and policymakers, including a number of the scientists who pioneered CRISPR, have called for caution and the need for public consultation and dialogue that also involves faith leaders, environmental activists, and advocates for patients and for people with disabilities. As society seeks a balance between the desire to realize the benefits of gene editing and a variety of other concerns, pgEd hopes to play a part in facilitating broad conversations that engage all communities and ensure that diverse values and voices are heard. <ref>[https://pged.org/genetic-modification-genome-editing-and-crispr/ Genetic Modification]</ref> Personal Genetics Education Project. | ||