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Chemical Genetics: Difference between revisions
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==Chemical Biology== | ==Chemical Biology== | ||
Chemical biology is a scientific discipline spanning the fields of chemistry and biology. The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and manipulation of biological systems. In contrast to biochemistry, which involves the study of the chemistry of biomolecules and regulation of biochemical pathways within and between cells, chemical biology deals with chemistry applied to biology (synthesis of biomolecules, simulation of biological systems etc.). <ref>[https://en.wikipedia.org/wiki/Chemical_biology Chemical Biology]</ref> | Chemical biology is a scientific discipline spanning the fields of chemistry and biology. The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and manipulation of biological systems. In contrast to biochemistry, which involves the study of the chemistry of biomolecules and regulation of biochemical pathways within and between cells, chemical biology deals with chemistry applied to biology (synthesis of biomolecules, simulation of biological systems etc.). <ref>[https://en.wikipedia.org/wiki/Chemical_biology Chemical Biology]</ref> | ||
==Directed evolution== | |||
A primary goal of protein engineering is the design of novel peptides or proteins with a desired structure and chemical activity. Because our knowledge of the relationship between primary sequence, structure, and function of proteins is limited, rational design of new proteins with engineered activities is extremely challenging. In directed evolution, repeated cycles of genetic diversification followed by a screening or selection process, can be used to mimic natural selection in the laboratory to design new proteins with a desired activity.<ref>[https://en.wikipedia.org/wiki/Chemical_biology Chemical Biology]</ref> | |||
==Drug Discovery to Pharma== | ==Drug Discovery to Pharma== | ||