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This is a very interesting and important excerpt in our understanding of the Leydig gland and is also fascinating from the standpoint of Edgar Cayce’s psychic process.  There are two important aspects to the question cited above: (1) The synonymous meaning of Leydig and Lyden; and (2) The location of this gland.
This is a very interesting and important excerpt in our understanding of the Leydig gland and is also fascinating from the standpoint of Edgar Cayce’s psychic process.  There are two important aspects to the question cited above: (1) The synonymous meaning of Leydig and Lyden; and (2) The location of this gland.


The first question is easy: Yes, both terms (Leydig and Lyden) refer to the same gland.  And in fact they are used interchangeably in the readings.  When the biological or strictly physiological aspect of the gland is emphasized, it is often called the Leydig, in reference to the man who discovered it and its biological function.  When the metaphysical or symbolic aspect of the gland is emphasized, the term “lyden” is typically used to signify the “closed” or “sealed” nature of the gland in its normal state.  Apparently, in historical times the word lyden meant sealed or shut.
The first question is easy: Yes, both terms (Leydig and Lyden) refer to the same gland.  And in fact they are used interchangeably in the readings.  When the biological or strictly physiological aspect of the gland is emphasized, it is often called the Leydig, in reference to the man who discovered it and its biological function.  When the metaphysical or symbolic aspect of the gland is emphasized, the term “lyden” is typically used to signify the closed or sealed nature of the gland in its normal state.  Apparently, in historical times the word lyden meant sealed or shut.


With regard to the location of this gland, it is a bit more complex.  The question itself may have contributed to the confusion.  Edgar Cayce’s psychic process was affected by many factors, including the consciousness, intent and understanding of the person asking the question.  So the wording and assumptions of the question could bias or influence the answer by Cayce.  This effect was described in the readings themselves with the insistence that people pay particular attention to how and why they asked questions.
With regard to the location of this gland, it is a bit more complex.  The question itself may have contributed to the confusion.  Edgar Cayce’s psychic process was affected by many factors, including the consciousness, intent and understanding of the person asking the question.  So the wording and assumptions of the question could bias or influence the answer by Cayce.  This effect was described in the readings themselves with the insistence that people pay particular attention to how and why they asked questions.
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The cells of Leydig discovered in 1850 by Dr. Leydig are interstitial cells located primarily in the reproductive glands of males and are best known for the production of testosterone, a sex hormone associated with masculinity.  Interstitial means that the cells of Leydig are scattered throughout the tissue rather than being grouped together as a unit.  So although the cells of Leydig secrete an important hormone (testosterone), properly speaking the cells of Leydig cannot be considered a gland, at least not as we normally define gland.  
The cells of Leydig discovered in 1850 by Dr. Leydig are interstitial cells located primarily in the reproductive glands of males and are best known for the production of testosterone, a sex hormone associated with masculinity.  Interstitial means that the cells of Leydig are scattered throughout the tissue rather than being grouped together as a unit.  So although the cells of Leydig secrete an important hormone (testosterone), properly speaking the cells of Leydig cannot be considered a gland, at least not as we normally define gland.  


On the other hand the Leydig gland, discovered in 1892, is a distinct unit of glandular tissue.  According to Franz Leydig, the Leydig gland is located in the mesonephros tissue in vertebrates.  This places it between the reproductive tract and kidneys.  Its function is unknown.  Dr. Leydig thought its role was to stimulate movement of spermatozoa.  So while the leydig gland is anatomically distinct and separate from the reproductive system, there may be a physiological connection between the leydig gland and the reproductive system (at least in males).  This is exactly how the Cayce readings described the anatomy and physiology of the Leydig (lyden) gland.  It is separate from the reproductive system anatomically (situated above in location) while its physiological activity (presumably via the chemicals it secretes) affects reproductive functioning.
On the other hand the Leydig gland, discovered in 1892, is a distinct unit of glandular tissue.  According to Franz Leydig, the Leydig gland is located in the mesonephros tissue in vertebrates.  This places it between the reproductive tract and [[Kidneys]].  Its function is unknown.  Dr. Leydig thought its role was to stimulate movement of spermatozoa.  So while the [[Leydig Gland]] is anatomically distinct and separate from the reproductive system, there may be a physiological connection between the Leydig Gland and the reproductive system (at least in males).  This is exactly how the Cayce readings described the anatomy and physiology of the Leydig (lyden) gland.  It is separate from the reproductive system anatomically (situated above in location) while its physiological activity (presumably via the chemicals it secretes) affects reproductive functioning.


Leydig's discoveries lay dormant for decades, as it was almost 100 years before medical science began serious research on the cells of Leydig in the 1950s.  Now there are hundreds of articles on Medline documenting the functions of these cells.  It is certainly understandable why Cayce scholars would have noted this large and growing body of research and drew an association with the readings’ use of the Leydig.
Leydig's discoveries lay dormant for decades, as it was almost 100 years before medical science began serious research on the cells of Leydig in the 1950s.  Now there are hundreds of articles on Medline documenting the functions of these cells.  It is certainly understandable why Cayce scholars would have noted this large and growing body of research and drew an association with the readings’ use of the Leydig.
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In contrast, the Leydig gland has yet to be rediscovered. When Edgar Cayce spoke of the Leydig or lyden gland, he always called it that – a gland.  He never called it the “cells of Leydig.” In one particularly explicit instance, he observed that this gland (which is normally about the size of a small pea) had become engorged to the size of a wren's egg.  The person was suffering from schizophrenia.
In contrast, the Leydig gland has yet to be rediscovered. When Edgar Cayce spoke of the Leydig or lyden gland, he always called it that – a gland.  He never called it the “cells of Leydig.” In one particularly explicit instance, he observed that this gland (which is normally about the size of a small pea) had become engorged to the size of a wren's egg.  The person was suffering from schizophrenia.


==What is the lyden [Leydig] gland and where located? ==
==What is the Lyden Gland [Leydig] and where located? ==
*(A)  Lyden [Leydig] meaning sealed; that gland from which gestation takes place when a body is created through coition, or inception, through conception of two bodies meeting in creating a body.  Located in and above the gland called genital glands, see?  In the male, above the glands corresponding to testes.  In the female, that above gland responding to testes in the male.  Here in THIS particular case, near the size of a wren's egg. Nominally should be about the size of a small pea.  (3997-1)
*(A)  Lyden [Leydig] meaning sealed; that gland from which gestation takes place when a body is created through coition, or inception, through conception of two bodies meeting in creating a body.  Located in and above the gland called genital glands, see?  In the male, above the glands corresponding to testes.  In the female, that above gland responding to testes in the male.  Here in THIS particular case, near the size of a wren's egg. Nominally should be about the size of a small pea.  (3997-1)


Here are several key points to consider based on this excerpt:
Here are several key points to consider based on this excerpt:


The lyden/Leydig is a discreet glandular entity, a ball of glandular tissue that is normally about the size of a small pea but had become swollen to the size of a wren’s egg.  This description only makes sense in relation to the Leydig gland and not the scattered, interstitial cells of Leydig.
The Lyden/Leydig is a discreet glandular entity, a ball of glandular tissue that is normally about the size of a small pea but had become swollen to the size of a wren’s egg.  This description only makes sense in relation to the Leydig gland and not the scattered, interstitial cells of Leydig.
In the male, the lyden/Leydig gland is located “above the gland called the genital glands.”  In the female, the lyden/Leydig is “above gland responding to testes in the male.”  So in both cases, the Leydig gland is anatomically above the reproductive system. This is consistent with the anatomical location of the Leydig gland as noted by Franz Leydig.  


Although anatomically above the reproductive system, the physiological activity of the Leydig affects (or is directed to) the reproductive organs in both males and females.  This is also consistent with the physiology of the Leydig gland as noted by Franz Leydig.  So the gland is above, but its activity passes through the reproductive organs.
In the male, the Lyden/Leydig gland is located “above the gland called the genital glands.”  In the female, the Lyden/Leydig is “above gland responding to testes in the male.”  So in both cases, the Leydig gland is anatomically above the reproductive system. This is consistent with the anatomical location of the Leydig gland as noted by Franz Leydig.
 
Although anatomically above the reproductive system, the physiological activity of the Leydig affects (or is directed to) the reproductive organs in both males and females.  This is also consistent with the physiology of the Leydig Gland as noted by Franz Leydig.  So the gland is above, but its activity passes through the reproductive organs.


From Cayce's perspective, pathology of the Leydig gland was sometimes associated with psychiatric and neurological conditions such as schizophrenia, manic-depressive disorder, and epilepsy.  Cayce also linked the Leydig gland to psychological and spiritual development and functioning.  Hence, opening the sealed or closed door associated with Leydig gland is a powerful and sacred process, that can sometimes result in unpleasant or even pathological (psychiatric/neurological) conditions if the [[Awakening]] process is becomes distorted. <ref>[(Posted on June 18, 2013 by David McMillin]</ref><ref>[https://www.mcmillinmedia.com/projects/seat/the%20leydig%20gland.html source link]</ref>
From Cayce's perspective, pathology of the Leydig gland was sometimes associated with psychiatric and neurological conditions such as schizophrenia, manic-depressive disorder, and epilepsy.  Cayce also linked the Leydig gland to psychological and spiritual development and functioning.  Hence, opening the sealed or closed door associated with Leydig gland is a powerful and sacred process, that can sometimes result in unpleasant or even pathological (psychiatric/neurological) conditions if the [[Awakening]] process is becomes distorted. <ref>[(Posted on June 18, 2013 by David McMillin]</ref><ref>[https://www.mcmillinmedia.com/projects/seat/the%20leydig%20gland.html source link]</ref>